There is a relative lack of reference data for elderly subjects 35, with existing data based on relatively small and unrepresentative samples. DLCO is well known to be positively correlated with altitude.28. In general, a PImax more negative than -80 cm water pressure and a PEmax more positive than +80 cm water pressure excludes important weakness of the respiratory muscles. Other pulmonary function test results can show how fast gas is exchanged from the lungs into the blood. Pulmonary function testing can be useful in evaluating respiratory complaints in HIV-infected patients. There are far less data regarding the effect of age on the ability to perform DLCO correctly. Furthermore, sitting height was not found to explain the variability observed in Asian subjects 22 and may not be appropriate for all ethnic groups. A 2-tailed P value of < .05 was considered significant. Normal values, however, rule out significant weakness. Differences in categorical data were examined with the Fisher exact test. What this study adds. Finally, these advances will have little impact unless disseminated and implemented in equipment software. We may need to adopt an entirely different approach in future to ascertain, for example, what is the minimum FEV1 required to sustain life and what is the level (whether in a “pathological” range or not) which does not limit our daily activities. This information can help your healthcare provider diagnose and decide the treatment of certain lung disorders. The author has disclosed no conflicts of interest. This study sought to determine if elderly patients are able to achieve both spirometry and diffusion capacity (DLCO) quality scores comparable to a younger adult population. The established collaborative initiatives could eventually be extended to include infants, elderly subjects and different ethnic groups in order to track the longitudinal development throughout the life course. Due to the complexity of the smoothly changing models, the equations cannot be expressed as simple polynomial equations, instead they require look-up tables. Additionally, because reference values … This study was a retrospective review of PFT data over a 22 month period (June 2011 through March 2013) in a hospital-based PFT laboratory (St Joseph Hospital, Nashua, New Hampshire). Interestingly, tests of executive function were found to be less predictive of outcome. Measurement of PEFR requires training to correctly use a meter and the normal expected value depends on the patient's sex, age, and height. During the same time frame, 178 control subjects attempted 178 spirometry and 122 DLCO tests. Sherman and colleagues3 assessed the ability of 65 elderly subjects with only mild cognitive impairment to perform spirometry. The laboratory's quality assurance program includes ongoing technologist performance surveillance and monthly and quarterly technologist performance feedback.17,18 Examination of the quality control records from the study period revealed no issues in terms of pneumotachograph or gas analyzer malfunction. The aim of the present study was to acquire a comprehensive set of reference values for cardiopulmonary responses to exercise and to evaluate possible associations with sex, age and body mass index (BMI). Most importantly, ethnicity itself is extremely difficult to define, especially given the growing multi-ethnic population, and may be politically sensitive with some nations now forbidding recording of such details. In the control group 88.5% (108/122) of the tests satisfied all the ATS/ERS acceptability and reproducibility criteria.15 Of the 14 DLCO tests that failed to satisfy all ATS/ERS criteria, 2 tests were performed correctly and were reproducible, but only failed to satisfy acceptability criteria because severe air-flow obstruction precluded capture of the alveolar sample within 4 seconds. As lung function is highly age dependent in adults, future studies should aim to include a larger number of older subjects to improve the accuracy with which we can interpret spirometry in this population. Age 2. Due to the wide range of 'normal' values and the high degree of variability, peak flow is not the recommended test to identify asthma. Hansen et al. Similar observations were made when data from 40,646 adults aged 17–90 yrs were re-examined 4. They show how well your lungs work. 5) and can be downloaded from www.growinglungs.org.uk 42. 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